Making mockery of what looked like a stiff 323-run target, the home team cantered to the win with 7.5 overs to spare, taking a 1-0 lead in the five-match series.
India have been invincible in the six-nation tournament as they defeated Pakistan twice, besides notching up wins against Hong Kong and Bangladesh.
India started their 2018 Asia Cup campaign with a 26-run win over Hong Kong, who rode on Nizakat Khan's 92-run knock to put up an impressive fight.
Sehwag pointed out that the Indian spinners will be up against batsmen who are brought up playing spin.
India begin their campaign against minnows Hong Kong on September 18 before taking on arch-rivals Pakistan in a marquee clash the next day.
The Virat Kohli-led No.1 Test side failed to put up a fight in the first two matches, but Chahal is hopeful that the visitors will bounce back in the remaining three matches.
Fast bowler Duanne Olivier was the wrecker-in-chief as he claimed six wickets to trigger the India collapse after the hosts resumed at overnight 322 for four.
The former India captain said the leg spinner has the skills and has been given the chance to prove himself in the ongoing 'A' series against South Africa.
However, it was a toil for the India A bowlers on the final day as it took them 88.5 overs to get the final six wickets.
It is widely believed that Chahal is being kept match-ready as the selectors have named senior squad for only three Test matches in England.
There is a school of thought that Ravindra Jadeja will be slowly eased out of the longer version if Chahal is able to show his skills in the four-day games.
This is not the first time that Indian players have been compared to animals by English commentators.
Chahal felt that unlike England innings when there wasn't much assistance for slow bowlers, the Lord's track helped home team spinners Rashid and Ali.
Dhoni was widely criticised for not showing initiative in his 37-ball 58 as India could only manage 236 in 50 overs after England posted 322 for seven.
"As clinical as it can be," Kohli described India's eight-wicket win in Nottingham that helped them take a 1-0 lead in the three-match series.
In an exclusive chat, former Team India skipper and IndiaTV's cricket expert and analyst, Sourav Ganguly, decoded what went wrong for the Men in Blue and how they can fight back to clinch the series.
The Men in Blue now have the chance to wrap up the T20I series early on this tour and another win in Cardiff will give them an unassailable 2-0 lead.
As India start their blockbuster series against England with the opening T20I on Tuesday, former India opener Virender Sehwag believes the pair of wrist spinners - Kuldeep Yadav and Yuzvendra Chahal will leave an impact on the pace-friendly wicket in Manchester. Speaking to IndiaTV on Cricket Ki Baat, Sehwag said captain Virat Kohli, who failed miserably on his last England tour in 2014, will score a lot of runs this time. For more sports news and updates: https://www.indiatvnews.com/sports
Chahal said he will look to repeat his heroics in London when his team takes on England in the first T20I of the three-match series at the Old Trafford, Manchester, on Tuesday.
India demolished Ireland by 143 runs to clinch the two-match T20I series 2-0 at The Village, Dublin.
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