The doctors were travelling by Innova to Agra for celebrating the birthday of Dr Harshad, who was driving the car when a tanker hit it from the rear near 88 milestones on the expressway.
The accident occurred at around 8:30 pm but the ambulances did not arrive till 10 pm.
Bollywood celebrities Varun Dhawan, Parineeti Chopra, Taapsee Pannu and Arjun Kapoor voiced their concerns over Delhi smog.
The horrifying incident was captured on camera. Watch video.
Jaiprakash Associates Ltd said it has an offer worth Rs 2,500 crore for hiving off the Yamuna Expressway.
Six-lane Yamuna Expressway connects Greater Noida with Agra. It is one of the longest six-lane controlled-access expressway stretch.
RSS chief Mohan Bhagwat was on his way to Vrindavan to attend a programme. He is safe.
There have been a staggering 4,054 accidents since the Expressway opened in August 2012.
Watch: 20 vehicles collide due to dense fog at Yamuna Expressway in Mathura, several hurt
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