The city of Milan erupted into a cacophony of car horns after the final whistle confirmed Inter as champion, and fans immediately started gathering in the main square in front of the cathedral to celebrate.
Antonio Conte, a lifelong Juventus fan and former coach and player, could wrest the Serie A title from the nine-time defending Italian champions and bring it to Inter Milan.
The rule, which would ban any team participating in a privately run competition from playing in domestic leagues, was approved unanimously by the FIGC council, which includes Inter Milan CEO Giuseppe Marotta.
Inter Milan can extend its advantage over second-place Milan to eight points with a win at Bologna later. It will also have played a match less than its city rival.
Lukaku was included in coach Roberto Martinez's squad last week but his availability had been unclear because of virus outbreak at the Serie A club.
Defender Milan Skriniar scored early in the second half and boosted Inter’s chances of winning its first Italian league title in more than a decade.
A coronavirus outbreak forced Torino players and staff into self-isolation that doesn't end until midnight Tuesday, hours after the scheduled kickoff against Lazio in Rome.
Juve moved up to third on the table, eight points behind Serie A leader Inter Milan, having played a match less.
Ronaldo had a lacklustre outing with the Portuguese superstar failing to bank on three chances that fell his way including two shot on the target while Insigne scores the winner from the spot for Napoli.
Ibrahimovic fired Milan ahead in the 30th minute with his 500th club goal and extended that tally in the second half.
Ronaldo turned 36 on Friday then showed little sign of slowing down as he scored and also hit the crossbar in the first half.
Cristiano Ronaldo took over the role of architect on the day as both the goals were results of move started by the Portuguese superstar.
Milan moved five points clear of second-place Inter Milan, which hosts Benevento later. Juventus is also playing later, at Sampdoria.
Juventus have moved back into the top four of Serie A as Arthur's maiden goal for the Bianconeri helped them beat Bologna 2-0 at Allianz Stadium.
Zlatan Ibrahimovic scored twice to help 10-man AC Milan win 2-0 at Cagliari on Monday and reclaim first place outright in Serie A.
Napoli moved third, three points behind Inter Milan and six back of league leader AC Milan.
Ronaldo sealed the win by running onto a long ball from Danilo, sprinting past the defence, and driving in a precise strike.
Juve broke the deadlock in the 18th minute as Paulo Dybala's fantastic back-heeled pass found Federico Chiesa who blasted in an angled drive.
Cristiano Ronaldo scored twice and set up another for Federico Chiesa as Juventus beat Udinese 4-1 as he becomes second all-time highest goal scorer ahead of Pele.
Cristiano Ronaldo scored two goals and set up another for Federico Chiesa as Juventus beat Udinese 4-1.
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