The champions are third in the league with a target now of overhauling Leicester a point away - rather than Liverpool who are 14 points in front of Man City.
Pep Guardiola went on to laud Sergio Aguero for being so humble despite being a big soccer star and said replacing Aguero will be his biggest challenge.
Guardiola says Aguero will not be fit for the derby match against Manchester United in the league on Dec. 7
Neither Sergio Aguero nor Angel Di Maria have played for Argentina since the latest Copa America in Brazil.
Manchester City dominated possession on the south coast but also survived some shaky moments.
Sergio Aguero has scored just once in four matches in this tournament, prompting doubts about whether he would hold his place in Argentina's attack alongside Lionel Messi and Lautaro Martinez.
Mauro Icardi has been a regular in Lionel Scaloni's squads but he recently lost his starting position at Inter because of a contract dispute and the Argentina coach prefers to pick players that get more playing time for their teams.
Sergio Aguero scored his 11th Premier League hat-trick as Manchester City humiliated Chelsea 6-0 at the Etihad.
Sala was travelling to Cardiff in a plane piloted by David Ibbotson, which went missing over the English Channel on January 21.
Despite the tight turnaround after the World Cup, Manchester City's attacking ruthlessness has not been blunted by fatigue or the English heatwave.
There's still a chance for Argentina to advance, but the South Americans have to win and their destiny is partly in the hands of other teams.
The Argentinian scored a hat-trick and a beautiful assist to Sergio Aguero that led his team to a 4-0 victory against Haiti in an International friendly.
Supporters from both clubs were involved in disturbances, while television pictures appeared to show a home supporter and striker Aguero involved in a physical exchange.
City showed no sign of a lack of confidence following the 4-3 loss at Liverpool last Sunday as Aguero was on point to net in his 11th hat-trick for the club.
The Argentine international, who has scored 130 goals for Manchester City, also said he has an option to extend the contract with his present club.
Maradona's former son-in-law became Manchester City's all-time top scorer with a goal in a 4-2 victory over Napoli on Wednesday, it seemed like there was a bit of destiny in the air.
City did not disclose the nature of 29-year-old Aguero's injuries but as media reports suggest the forward was involved in a car crash.
Pep Guardiola's side made it 15 goals in three games as it followed up thumping victories over Liverpool and Feyernood to end Watford's unbeaten start to the league.
Manchester City took 70 minutes to break through Brighton's resistance and were aided by the English Premier League newcomer's carelessness to ensure they left the southern seaside resort with a 2-0 victory on Saturday.
London: Premier League leader Chelsea left it late to beat Everton 1-0 on Wednesday and maintain its seven-point advantage over Manchester City as the champions won 4-1 at Stoke.Willian's 89th-minute winner for Chelsea came a
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