The three-time former champion Saina used her powerful smashes to telling effect, registering a 21-18 21-15 win against Sindhu, a two-time winner, in the summit clash.
A former champion, Sindhu took time to get into the groove before claiming a 21-11 21-13 win over Malvika, who is a gold medallist at the South Asian U-21 Championship in Nepal.
Besides the top names, over 400 players from 29 states and 2 union territories will take part in the event.
New Delhi: Three-time national champion Chetan Anand began his comeback from an injury curtailed season with a comfortable 21-5, 21-15 victory over Vishal Garg of Assam in the second qualifying round of the 78th Senior
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