Dominic Calvert-Lewin's 13th league goal of the season for Everton after only three minutes came courtesy of a rebounded clearance while Bruno Fernandes' superb start to life at United was given a helping hand by Pickford.
The 22-year-old Rashford sustained his latest injury after being introduced as a second-half substitute in Wednesday's 1-0 FA Cup third-round replay win over Wolves.
The 22-year-old Rashford opened the scoring after 27 minutes of a one-sided encounter with a volley at the far post, then added a penalty after Brandon Williams was brought down by Norwich goalkeeper Tim Krul.
The loss at Emirates Stadium extended Arsenal’s winless streak to seven games across all competitions — its worst run since 1992 — increasing the pressure on coach Unai Emery after a series of disappointing results.
Bournemouth provisionally climbed to sixth in the table with the win, which was sealed by Joshua King's goal shortly before halftime.
The draw was a major blow for Manchester United's hopes of Champions League qualification.
A win at Molineux would have lifted United into third place but Ole Gunnar Solskjaer's team stayed in fifth.
After Barcelona set prices at 118 euros ($134) for visiting Man United fans, the English club retaliated with an equivalent 102-pound price for away fans at Old Trafford.
United was without its entire first-choice front three as well as key midfielders Nemanja Matic and Ander Herrera.
The club did not comment on the reports about takeover interest from Saudi Arabia ahead of the minister's denial.
With a 10th hat trick in the Premier League alone, Aguero is only one behind the retired Alan Shearer's record.
Solskjaer is looking to become just the fifth manager in United's history to start with back-to-back league wins.
Their wins nicely set up a Manchester derby game in the Premier League on Sunday.
Juventus delivered a powerful performance that extended its unbeaten start to the season to 11 games.
Coming off a superb win against the league leaders in the previous weekend, Mourinho's Reds faltered against a determined West Brom, who had nothing to lose.
Ibrahimovic, who joined Jose Mourinho's Manchester United in 2016, arrived on a free transfer but has had an aggravating and troublesome journey so far.
The winger has made a bright start as he scored on his debut and Sanchez has set a new record on social media as the deal announcement post was 'the biggest United post on Instagram'.
With players such as Paul Pogba, Nemanja Matic and Ander Hererra being the first names on the team sheet, Mata's starting days are mostly but over but Mourinho has always relied on the Spaniard to deliver.
Revenge was 108 years in the making for Bristol City, which lost to United in its only major final in the 1909 FA Cup.
The Manchester United midfielder recently took to Instagram to upload a new cut as the Frenchman is currently sidelined from the squad due to a red card.
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