The win widened the gap to closest challenger Leicester even further after Brendan Rodgers' team was held to a 1-1 home draw by Norwich. The Reds have won 16 of 17 league games so far, with one draw.
Klopp joined Liverpool in October 2015 and led the team to the Champions League title last season.
Current European champions Liverpool are eyeing a move for Japanese midfielder Takumi Minamino, who currently plays for Salzburg.
Salzburg sporting director Christoph Freund said his club is in talks with Liverpool over the transfer of Minamino, who impressed in two games between the teams in the group stage of the Champions League this season.
Naby Keita, a former Salzburg player, headed in the opening goal in the 57th minute before Mohamed Salah rounded the goalkeeper and squeezed home a finish with his weaker right foot from an acute angle near the byline.
Lovren picked the injury during his club's 3-0 win over Bournemouth in Premier League on Saturday.
Liverpool strengthened their grip on the first place with an easy 3-0 win over Bournemouth, while Son Heung-min stole the show with an excellent solo goal in 5-0 rout of Burnley.
Everton's dismal defeat in its biggest game of this and any season simply made it inevitable.
Liverpool stayed eight points clear of Leicester at the top of the Premier League, while Everton dropped into the relegation zone.
Van Dijk, who helped Liverpool to win the title of the Champions League last season, lost to FC Barcelona star forward Lionel Messi in the 2019 Ballon d'Or race recently.
Merseyside derby awaits in the third round of the FA Cup as Liverpool host Everton, while Manchester United will take on Wolverhampton Wanderers.
Hours after City’s shaky defence conceded an 88th-minute equalizer in a 2-2 draw at Newcastle, Van Dijk ventured forward to power home two headed goals from free-kicks and lead Liverpool to a 2-1 win over Brighton.
Goals from Alex Oxlade-Chamberlain and Georginio Wijnaldum secured a scrappy 2-1 win over Genk as Liverpool seized control of Group E on Tuesday.
Left-back Andy Robertson charged in from the flank to meet Mane's cross in the 87th minute with Liverpool facing the imminent end of its unbeaten record in the league.
Defending champions Manchester City will take on Oxford United while Colchester United, the lowest-ranked side left in the tournament, make a trip to Old Trafford.
Liverpool knocked out Arsenal in the pre-quarters of the League Cup 5-4 via penalties after the game ended 5-5 after normal time while Marcus Rashford's brace sent Manchester United to the next round.
Liverpool are chasing their first league title since 1990. For Tottenham, it is finding a way to rise from 11th place closer to the top four where they have finished for four consecutive seasons.
With six points from three matches, Liverpool remained in second place in Group E — one point behind Napoli, which beat Salzburg 3-2.
Manchester United vs Liverpool, Premier League Live Streaming: Find full details on when and where to watch MUN vs LIV online on Hotstar and TV Telecast on Star Sports.
Paul Pogba has an ankle problem and Ole Gunnar Solskjaer confirmed that the 26-year-old has had a setback in his recovery.
Top News
Latest News
