The Spanish club is already thinking about next season, and it appears the changes will start at the top, with coach Santiago Solari unlikely to keep his job.
Highlighting the difficulty replacing Alex Ferguson, United has now spent 33.2 million pounds dismissing the three managers hired since he retired in 2013.
Mourinho appeared before a judge in a Madrid court to confirm the plea agreement he had reached with prosecutors and has to pay a fine of nearly 2 million euros.
Mourinho said that he is not someone who goes on to reveal the details about what actually happened.
Solskjaer will take charge of the first team with immediate effect and will remain in place while the club conducts a thorough recruitment process.
Mourinho, who was brought in 2016 as Luis Van Gaal's replacement, endured a poor run in this season, which saw the Red Devils below the top 6.
With a few minutes left of United's 3-1 loss at Anfield, cameras panned to Pogba sitting on the bench, his arms folded, the hood of his training top shielding his face from the driving rain on a bitterly cold day.
Sanchez has so far had a disappointing season at home, scoring just one goal in the Premier League in 10 appearances.
Jose Mourinho picked up a basket of water bottles and threw them to the ground after Marouane Fellaini scored in stoppage time to earn Manchester United a 1-0 win over Young Boys.
Completely outplayed by English football's dominant force, Mourinho has little prospect of dethroning City as champions.
Mourinho is unpopular among Juventus fans after managing bitter rival Inter Milan for three years.
In the high octane clash between the two English giants, Barkley robbed United of three vital points after scoring at death, levelling scores at Stamford Bridge.
The goals have dried up (it's nine games without scoring, his longest drought in the red of United). His touch has deserted him. He might even be trying too hard.
The Portuguese coach appears to have recovered confidence after a 3-2 home win against Newcastle and a 2-2 draw away to Chelsea.
Three goals in the last 20 minutes by Mata, Martial and Sanchez earned United its first Premier League win since the opening round, as it rallied from conceding two goals in the first 10 minutes.
With 10 points from seven games, Mourinho has matched the club's previous worst Premier League start under Ferguson's successor, David Moyes.
Mourinho insisted that it wasn't because of a dispute with the World Cup-winning France midfielder who returned to United in 2016.
In a shootout after the game ended 2-2 on Tuesday, the teams scored 15 consecutive penalties before United defender Phil Jones' effort was saved by goalkeeper Scott Carson.
Manchester United were simply outclassed by Mauricio Pochettino's Spurs in the second half, despite the Red Devils bagging most of the possession and attempts on goal.
The 22-year-old French footballer now faces a fine up to £180,000 under the supervision of Mourinho’s staff.
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