It may depend on whether the various broadcasters, who paid 25 million pounds for the rights to the Old Trafford Test, would be willing to settle for two evenings' cricket rather than five full days.
Shastri has been in quarantine since September 4 and is expected to complete his 10-day isolation period along with Arun and Sridhar on Monday.
The final match of the series was cancelled when a physio in the Indian camp tested positive ahead of the game, making the visiting players apprehensive, though all of them tested negative.
Shastri himself was the first to test positive for the virus, followed by bowling coach Bharat Arun and fielding coach R Sridhar too testing positive.
ECB is going to lose 40 million pound if the match is declared abandoned due to COVID-19.
After a COVID-19 outbreak in the Indian camp, senior players expressed their apprehensions to both BCCI and ECB on playing and the Test was called off with India leading 2-1 after four Tests.
Shastri's book, titled 'Stargazing: The Players in My Life', had a launch event on August 31 in London, two days before the start of the fourth Test at The Oval
The 39-year-old Anderson bagged 15 wickets, behind Jasprit Bumrah (18 wickets) and Ollie Robinson (21 wickets) for most wickets in the series.
The fifth Test was called off just hours before it was due to begin due to Covid-19 outbreak concerns in the Indian team after the second physiotherapist tested positive.
Vaughan's comments come after the fifth Test between the two teams was cancelled on Friday due to fears of COVID-19 cases increasing inside the Indian camp.
The former England skipper added that he didn't want to blame the Indian cricketers for deciding not to play the fifth Test as life inside the bio-bubble is very tough.
The fifth Test between India and England here was called-off hours before its start on Friday after a COVID-19 outbreak in the visiting team's camp.
The most likely window for the rescheduled game is July next year when India would be in England for a limited-overs assignment.
Ravindra Jadeja, Cheteshwar Pujara, Shardul Thakur, Moeen Ali and Sam Curran are part of the CSK squad which has already started training ahead of the IPL resuming September 19.
It was after that book release event at a five-star facility ahead of the fourth Test that Shastri along with bowling coach Bharat Arun, fielding coach R Sridhar and physio Nitin Patel tested positive
Just hours before play was set to begin at the Old Trafford, the game's cancellation was announced due to India's fears about a potential Covid outbreak despite all the players' latest PCR tests returning negative results.
Tom Harrison said the developments of the past couple of days have been devastating and everything necessary was done to convince the Indian players.
The match was called off due to the Indian players' reluctance to play it following emergence of a fresh Covid-19 positive case.
Karthik, who is now part of the IPL bubble, had commentated for the first three Tests before he left to join the KKR squad in the UAE.
The fifth and final Test between India and England has been cancelled, the England and Wales Cricket Board has confirmed. in a statement released on their official website, the ECB said that the India are "regrettably unable to field a team," following the increase in the number of COVID-19 cases in the camp.
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