The Brazilian playmaker came off the bench to score a late equaliser on his debut for Aston Villa in a 2-2 draw against Manchester United.
Brazil national team doctor Rodrigo Lasmar performed the operation on Monday; removing a cyst on the 28-year-old footballer's left knee.
The Brazil midfielder hasn't been able to show the type of playmaking ability that made him a star at Liverpool and prompted the Spanish club to sign him.
Coutinho, who has a left thigh injury, and Marcelo, who injured his right thigh, would have started the games, but Alex Sandro and Augusto have been named as their replacements.
It seems unfathomable that two years ago the five-time world champions were in danger of missing football's showpiece event in Russia.
Wijnaldum said they would have been happy if he made the move to FC Barcelona as it could have helped his career.
There was a lot of speculation surrounding Coutinho as to where he would be playing this season as he missed the start of the season.
FC Barcelona had targetted the Brazilian player from the start of the summer transfer window but Liverpool kept rejecting the bids made despite Coutinho handing in his transfer request.
Liverpool said this week that Coutinho was also ill. He will miss the English Premier League game against Arsenal on Sunday.
Liverpool, England: English Premier League leader Liverpool will be without Philippe Coutinho until the end of October after the Brazilian playmaker was booked in for surgery on a shoulder injury.The 21-year-old Coutinho was forced off
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