This latest goal burst could end Chelsea's title defense, barring the type of second-leg collapse by Madrid that Paris Saint-Germain endured last month at the the Santiago Bernabéu Stadium.
Kevin De Bruyne scored the only goal to give Manchester City a 1-0 win over Atletico Madrid in the first leg of their Champions League quarterfinal.
Real Madrid will likely be without coach Carlo Ancelotti for the first leg of the Champions League quarterfinals against Chelsea because of COVID-19. Ancelotti tested positive for the coronavirus last week and did not travel to London with the rest of the squad on Tuesday.
U.S. international Christian Pulisic converted one of Chelsea's rare chances and Cesar Azpilicueta added another goal on Wednesday to help the embattled Premier League club progress with a 2-1 win at Lille, and 4-1 on aggregate.
Led by an excellent Phil Foden in a false No 9 role, City pressed hard up the pitch at Jan Breydel stadium and was rewarded with first-half goals from Joao Cancelo and Riyad Mahrez. Kyle Walker, substitute Cole Palmer — on his tournament debut — and Mahrez with his second of the night completed the scoring after the interval.
Carlo Ancelotti's men travel to Ukraine after their La Liga game at home to Athletic Bilbao was postponed to allow their South American players more time to recover after the international break.
The Catalan club followed its 3-0 opening loss against Bayern Munich with another 3-0 defeat at Benfica on Wednesday.
Ronaldo made his most decisive intervention with virtually the last kick of the game at Old Trafford to complete United's dramatic comeback in a 2-1 victory over Villarreal.
Griezmann leveled six minutes from time and Atlético was awarded a penalty that Suárez struck confidently down the middle in the seventh minute of stoppage with the last of the visitor's 22 shots on Tuesday.
Sébastien Thill scored a 90th-minute winner as the newcomers stunned Real Madrid 2-1 at the Santiago Bernabéu Stadium on Tuesday.
Lionel Messi scored his first goal for Paris Saint-Germain during the Champions League game against Manchester City on Tuesday.
Lionel Messi is expected to be back in the attack against Manchester City in the Champions League as the Argentine shakes off a minor knee injury that sidelined him for two games.
Griezmann will get another chance to win back the hearts of Atlético’s faithful on Saturday against the unbeaten Athletic Bilbao.
Jordan Henderson capped Liverpool's second-half comeback with a brilliantly controlled finish to clinch a 3-2 win over AC Milan.
French forwards flourished with Sébastien Haller scoring four for Ajax in a 5-1 rout at Sporting Lisbon and Christopher Nkunku netting all of Leipzig’s goals in a 6-3 loss to Manchester City.
Club Brugge defence as it must cope with Paris Saint-Germain's attacking armada of Lionel Messi, Neymar and Kylian Mbappe.
Cristiano Ronaldo scored but lost on his return with Manchester United, then Robert Lewandowski and Romelu Lukaku both led their teams to victory in their opening games.
The 39-year-old striker suffered an inflammation to his Achilles tendon after his comeback match against Lazio on Sunday, following a four-month injury layoff.
The Champions League group stage starts Tuesday with a match between traditional heavyweights Barcelona and Bayern Munich, but big-spending upstarts elsewhere are the title favourites this season.
Six-time winner Bayern Munich and five-time champion Barcelona are in Group E with Benfica and Dynamo Kyiv.
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