Bhambri and Sharan, who had also teamed up at the inaugural Maharashtra Open, sent Raja and Martin packing with a 6-3, 5-7 and 6-4 win in the opening round of the Roland Garros.
Djokovic, currently ranked 22 in the world, will now face 13th seeded Spaniard Roberto Bautista Agut in the Round of 32, scheduled to be played on Friday.
Bopanna and his French partner Roger-Vasselin began their Roland Garros campaign with a comfortable win over the American team of Taylor Fritz and Frances Tiafoe.
Shapovalov registered a 7-5, 6-4, 6-2 victory over 59th-ranked John Millman of Australia in his first Grand Slam match as a seeded player at Roland Garros.
There also is a message Serena wanted to send about self-worth and feeling powerful as she returned to Grand Slam action with a first-round victory at Roland Garros on Tuesday, about nine months after giving birth to a daughter.
Competing as a mom for the first time at a major, and only about nine months since giving birth to her daughter, Williams beat 70th-ranked Kristyna Pliskova of the Czech Republic 7-6 (4), 6-4 at Roland Garros.
Rohan Bopanna began his men's doubles campaign with an easy win along with French partner Edouard Roger-Vasselin in Paris on Tuesday.
Nadal improved his Paris record to 80-2 with a 6-4, 6-3, 7-6 (9) rain-interrupted win completed over two days on Court Philippe Chatrier.
Argentine Trungelliti, returned home to Barcelona after losing in qualifying last week but made the dash to the French capital when Australian Nick Kyrgios pulled out of his tie against Bernard Tomic with an elbow injury.
Returning to the place where he claimed the second of his three Grand Slam titles did not help Wawrinka shake off his poor form.
The top-ranked Spaniard faces Simone Bolelli of Italy on Court Philippe Chatrier.
Stephens advanced at Roland Garros with a 6-2, 6-0 victory over Arantxa Rus of the Netherlands.
Ninth-seeded American Venus Williams lost 6-4, 7-5 to Wang Qiang of China in the first round of French Open.
Despite an inconsistent clay-court season so far from Muguruza, the two-time Grand Slam champion from Spain is among the top contenders at Roland Garros.
For the second year in a row, Federer opted to quit the entire clay season, where Nadal is always the favorite, to focus on grass court-play.
The American sisters were handed a wild-card entry on Thursday into the tournament which they won together in 1999 and in 2010.
Serena Williams resumes her comeback after maternity leave following two consecutive losses in March.
Simona Halep needs to reach the semifinals in Paris to have a chance of keeping her top spot in the rankings.
Wawrinka was swept aside by Marton Fucsovics of Hungary 6-4, 6-0 in the quarterfinals for his first defeat in front of home fans at Geneva since 2015.
Chung, who had to retire in his semifinal against eventual champion Roger Federer at Melbourne Park in January because of severe blisters, said he had been carrying the ankle injury through the clay-court season.
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