Napoli had fought back from 3-0 down thanks to goals from three of its new signings but Kalidou Koulibaly's attempted clearance looped into his own net in stoppage time.
Liverpool defeated Burnley 3-0 while Sheffield United came back from being 2-0 down to earn a point against Chelsea at Stamford Bridge.
Manchester United couldn't put away any of their late chances, though, leaving the opening-weekend 4-0 over Chelsea as their only win so far.
Manchester City's third victory in four matches this season came at a cost with Laporte carried off on a stretcher late in the first half with a right knee injury.
Lukaku had scored 42 goals for United. However, after he netted 15 goals last season, former United defender Gary Neville had criticised his physical condition, saying that the Belgian striker weighed over 100 kg.
Monreal has agreed a two-year contract with the San Sebastian based outfit, making a return to La Liga after six years in England
Juventus did not estimate how long Giorgio Chiellini will be out for but the injury normally requires three to six months of recovery, depending on the severity of the tear.
Manchester United was drawn Friday into Group L with AZ Alkmaar, Partizan Belgrade and Astana, which is more than six hours by air from Manchester.
Chris Smalling signed for AS Roma on a season-long loan deal a few days after Alexis Sanchez signed for Inter Milan on loan.
Entering the UEFA awards as a favourite to win the trophy, Van Dijk snatched victory from Lionel Messi's hands once again in a reminiscence of the UCL semifinal last season.
Ronaldo also admitted that he missed playing in Spain and the rivalry with Messi.
Bayern Munich striker Robert Lewandowski has committed his future with the German champions till June 2023.
Alexis Sanchez will reunite with Romelu Lukaku at Inter Milan, who left Manchester United in the summer transfer window.
Luis Enrique, the former Barcelona and Spain manager, announced the tragic death of his daughter on Friday.
It will be tough for PSG after being paired in a group with a Real Madrid side chasing a record-extending 14th European crown.
Dressed in a red shirt and grey cap, Cantona started off by invoking William Shakespeare's King Lear: "As flies to wanton boys, we are for the gods."
Van Dijk was the star performer for Liverpool in the 2018-19 Champions League-winning campaign.
Lewandowski, who joined Bayern from league rival Borussia Dortmund in 2014, has started the season with five goals in two Bundesliga games, making him the only Bayern player to have scored in the league so far.
Speculation has mounted that Keylor Navas will leave the Spanish capital in the coming days, with Paris Saint Germain (PSG) among the frontrunners to sign him.
Liverpool, Manchester City, Chelsea are all in the pot of eight top-seeded teams along with Barcelona, Juventus, Bayern Munich, Paris Saint-Germain and Zenit St. Petersburg.
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