Myburgh blazed seven fours and two sixes in his 55 as the Netherlands eased to 152-4 with seven balls to spare after Malik's three late strikes had bowled out UAE for 151 in 19.5 overs.
The Netherlands joined Ireland at the top of Group B after the Irishmen stunned Zimbabwe by three wickets.
Shaiman Anwar top scored with 32 for UAE as none of the middle-order batsmen could capitalize on steady starts.
Myburgh and Michael Swart set the tone with a rollicking start of 69 runs off 40 balls with Tom Cooper remaining unbeaten on 34 off 26 balls.
