He made his debut in the Second Test of the series on 9 October 2010 at Bangalore after both Gautam Gambhir and VVS Laxman were down with injuries sustained in the First Test.
While Laxman was off the field injured in the First Test, Pujara took two catches at silly point as a substitute.
Pujara's first Test innings was short however as he scored four runs but was adjudged leg before wicket to Mitchell Johnson on the third ball he faced.
