"This time people are with me and they will support me to defeat both the JD-U and BJP in Lok Sabha polls," he claimed.
Pappu Yadav won thrice from Purnia - 1991, 1996 and 1999 - and won the 2004 Madhepura bypolls.
His wife and former MP Ranjita Ranjan is likely to contest on a Congress ticket, sources said.
Last year, citing lack of evidence, the Patna High Court acquitted Yadav in a case related to the killing of Communist Party of India-Marxist leader Ajit Sarkar in May 1998.