In 1972, Jayalalithaa acted in Pattikada Pattanama opposite Sivaji Ganesan, which went onto win the National Film Award for Best Feature Film in Tamil in 1973. She also got Filmfare Award for Best Actress for the same film.
Jayalalithaa's last film was Nadhiyai Thedi Vandha Kadal in 1980.
Jayalalithaa also tried her luck in Bollywood and acted in a few ‘Hindi' films that included ‘Izzat' in which she was paired with Dharmendra.
M G Ramachandran became the mentor of Jayalalithaa not only in film industry but also in her personal and political life. MGR had already joined politics and had become CM of Tamil Nadu in 1977. She started to groom Jayalalithaa in politics and made her the propaganda secretary of the party.