Maoists used eight cylinder bombs to blast the school building. Police have also recovered three live cane bombs from the school premises.
A police official said that Central Reserve Police Force (CRPF) personnel were camping in the school for last few days ahead of polls in the neighbouring Jamui constituency.
"When Maoists attacked and blasted school building, the CRPF personnel were out on duty," the police official said.
It is not the first school destroyed by the left-wing rebels. In the last two years, dozens of schools were targeted by Maoists.