Zardari, as President, remained in the eye of storm for holding dual office and faced allegations of using the President's house for partisan politics and ignoring key issues facing the country.
He faced a strong and assertive judiciary which pursued him over multi-million-dollar corruption cases against him in Switzerland.
The casualty of the struggle was then Prime Minister Yousuf Raza Gilani, who was sacked for refusing to ask Switzerland to reopen the cases.
Another big crisis for him was the ‘Memogate scandal' and also the unilateral US operation in May, 2011, in the garrison city of Abbottabad that killed al-Qaeda chief Osama bin Laden.
While the President's post is largely ceremonial, Zardari, as the chief of the then-ruling PPP, played an active role in the functioning of the government.
However, he later had to give up the party post after pressure from the judiciary.
His detractors blame him for the weak economic and security scenario of the country.