4. Cleopatra murdered two of her siblings: Cleopatra had Marcus Antonius kill her younger sister, Arsinoë IV when it became apparent that opposition forces were rallying around her.
Her brothers, Ptolemy XIII and Ptolemy XIV, both ruled with her for a short time; however, Ptolemy XIII died in an ensuing battle while Cleopatra allegedly poisoned Ptolemy XIV after the birth of her son, Caesarion.