Guarded by a security detail reminiscent of a presidential visit, police enforced rolling street and sidewalk closures as early as Thursday night in some locations and discouraged spectators from swarming side streets.
The behemoth transport has caused headaches for shopkeepers along the route who counted on cheering crowds jamming the curbs to boost business.
In the days leading up to Endeavour's move, the owners of Randy's Donuts sold shuttle-shaped pastries emblazoned with the NASA logo and even hung a shuttle replica inside the giant doughnut hole sign visible from the busy Interstate 405.