According to Blitz, a weekly tabloid published from Dhaka, Hina Rabbani Khar, the married foreign minister, who has two young children with her millionaire husband, and Bilawal Bhutto Zardari, want to get married and have been regularly talking on the telephone and sending one another cards.
The tabloid claimed President Asif Ali Zardari is firmly opposed to their alleged relationship and had sought details of their mobile telephone conversations to establish the facts.
The ISPR spokesman said it is handiwork of those who want to weaken the state by creating misunderstanding between various institutions.
"It is not something new because such people have been fabricating misleading and impish stories in the past as well", he added.
The spokesman said: "The British daily needs to behave more responsibly and confirm veracity of information from respective entities before printing such malicious stories."
The British Daily Telgraph had reported: "Senior PPP figures on Thursday said they believed the claims were part of a plot by the country's feared Inter-Service Intelligence [ISI] agency to damage Ms Rabbani Khar's reputation because it blames her for her part in facilitating a UN investigation into thousands of missing people detained by the security forces.