North Korean threats have become more common as tensions have escalated following a rocket launch by Pyongyang in December and its third nuclear test on Feb. 12.
Both acts defied three Security Council resolutions that bar North Korea from testing or using nuclear or ballistic missile technology and from importing or exporting material for these programs.
U.S. U.N. Ambassador Susan Rice said the proposed resolution, to be voted on at 10 a.m. EST (1500 GMT), would impose some of the strongest sanctions ever ordered by the United Nations.
The final version of the draft resolution, released Wednesday, identified three individuals, one corporation and one organization that would be added to the U.N. sanctions list if the measure is approved.
The targets include top officials at a company that is the country's primary arms dealer and main exporter of ballistic missile-related equipment, and a national organization responsible for research and development of missiles and probably nuclear weapons.