At least 52 people, including women and children, were killed and more than 100 others injured in a suicide bombing at a popular sufi shrine in Pakistan's restive Balochistan province on Saturday.
The attack, carried out by a 14-year-old boy, was claimed by the Islamic State terror group.
The blast occurred in the remote Hub region in Khuzdar district of the province while devotees were participating in a Sufi dance called "dhamaal" at Dargah Shah Noorani.
Balochistan Home Minister Sarfaraz Bugti said ambulances and rescue teams had rushed to site.
"The rescue operations are going on and the casualties could rise as some people are still trapped at the place where the blast took place," Bugti said.
Some local media reports put the death toll as high as 62. The target of the attack was the area where devotees perform 'dhamaal'. The blast site is situated some 250 km away from Karachi. The blast happened when about 500 to 600 devotees were present at shrine.
Abdur Rasool, an official at the province's home ministry, said rescuers were transporting the wounded to hospitals and the dead to local morgues, but were struggling in the difficult mountainous terrain, some 350 kilometers (217 miles) south of the provincial capital, Quetta.
The blast targeted worshippers as they were in the throes of their devotional "dhamal" dance, and the courtyard at the time was packed with families, women and children.
The blast comes ahead of the Prime Minister Nawaz Sharif's pre-planned trip to the province tomorrow, where he will see off the first Chinese shipping consignment to Africa from Gwadar port.
The Islamic State group's statement on the IS-affiliated Aamaq news agency said the suicide attack had targeted "Shiites."
The shrine is frequented by both Pakistan's Sunni Muslim majority and Shiite minority. IS considers all Shiite Muslims heretics.
"35 dead and 95 wounded Shiite visitors in...operation attack by the Islamic State fighter that targeted a shrine in a city in Balochistan," the agency said.
The Express Tribune quoted police sources as saying that the blast was a suicide attack carried out by a 14-year-old boy. Colonel Junaid Kakar of the Frontier Corps also told the media that it appeared to be the work of a suicide bomber.
"All evidences point to a suicide bombing," he said.
Rrescuers were facing difficulty in accessing the site asthe shrine is located in a remote area.
Women and children were among those killed in the blast. "The shrine is located some 250 kilometres from Karachi in the remote mountains of Uthal and our vehicles have been dispatched there to carry out rescue operations and shift the injured to the hospitals," said Hakeen Lassi, an official of the Edhi Trust Foundation.
Local tehsildar Javed Iqbal said security arrangements at the shrine were not proper.
"It is sad that although thousands of devotees from Karachi and other parts of the country visit the shrine everyday but there are no medical emergency facilities or ambulances at the site," he said.
He said the devotees take part in the 'dhamaal' everyday after sunset and the blast took place close to where they were dancing inside the compound of the shrine.
President Mamnoon Hussain and Prime Minister Nawaz Sharif strongly condemned the bomb blast and directed authorities to speed up the rescue activities.
One female witness, who was not identified by name, told the GEO television channel that a "big bang" took place in the midst of the dhamal dance in the shrine's courtyard. "I don't know how I escaped unhurt," she said. "It was like a hell all around."
A doctor at an area hospital told a local television station that the number of wounded being brought in had overwhelmed the hospital's capacity.
"We don't have sufficient space so several people were treated outside on the ground," the doctor said adding that, "Several wounded people have lost limbs."
A military statement said that four army medical teams and 45 army ambulances had been dispatched to the scene to assist.
This is the third major incident of a bombing in the province since August.
In August, about 70 people were killed in a suicide bomb attack outside the civil hospital in the provincial capital Quetta. Last month, 64 police cadets and two army men were killed when three terrorists raided a police training centre in Quetta.
(With PTI inputs)