Senior police and railway officials rushed to the scene. Vizianagaram district collector Kantilal Dande is supervising the rescue and relief work.
Chief Minister N. Kiran Kumar Reddy, who is in Bangalore, expressed shock and anguish over the mishap.
He directed the collector, superintendent of police and other top officials to supervise rescue and relief operations.
According to a statement from the chief minister's office, he asked officials to provide the best treatment to the injured.