The movement will move towards southern India for three months and later to northern regions for three months, educating people and mobilising support ahead of the Lok Sabha polls.
The Yamuna Rakshak Dal leaders said both the central and state governments have forgotten the assurances given.
Drains continue to open into the Yamuna adding to the pollution in Delhi.
They said central government representatives had assured them that a parallel drain would be built along the river to divert untreated waste water but nothing has been done.
The Uttar Pradesh state government had also given an assurance that a pipeline would be laid from Vrindavan to Mathura and similarly in Agra, but no action has been taken, they said.