However, the former "Friends" star wasn't so confident about taking on the role when she first began shooting for the film.
"I just had to do it. They rolled the cameras and I had to bite the bullet. It was a little uncomfortable at first, but then you get into it.
"You're on the set and there's three cameras a bunch of crew, so yeah, it's a little intimidating at first," she said.
Aniston stars alongside actors Jason Sudeikis, Emma Roberts and Will Poulter in the film.
"We're The Millers" will hit the Indian screens Aug 30.