The Rams' high-powered offense took a couple of big hits.
Los Angeles' leading receivers, Brandin Cooks and Cooper Kupp, were both lost to concussions late in the first half as the Rams turned to Robert Woods and a cast of lesser-known characters to beat the Seattle Seahawks 33-31 on Sunday.
Cooks was hit hard by Tedric Thompson as he came across the field. Most of the hit was with Thompson's shoulder, but there was some helmet-to-helmet impact and Cooks appeared to be immediately knocked out. He eventually jogged off the field on his own but was ruled out early in the second half.
Kupp was also lost with a concussion, although it wasn't immediately clear when he got hurt. Kupp was in on a desperation throw into the end zone on the final play of the first half, but didn't rejoin his teammates to start the third quarter.
The Jacksonville Jaguars, meanwhile, suffered injuries that will test their depth on the offensive line and at running back.
The Jaguars lost left tackle Cam Robinson for the season last month with a knee injury , and left tackle Josh Wells left Sunday's loss in Kansas City with an injured groin in the first half. Running back Leonard Fournette missed the game with a hamstring injury that has limited him this season, and Corey Grant hurt a foot and also left in the first half.
Luckily, cornerback Jalen Ramsey returned after taking a knee to the helmet on the opening series.
Kansas City lost four defensive players to injuries in the first half against Jacksonville with linebackers Justin Houston (hamstring) and Tanoh Kpassagnon (ankle) and free safeties Armani Watts (groin) and Eric Murray (lower leg) not returning.
The Chiefs' most significant injury might have come in the final minutes, when right guard Laurent Duvernay-Tardif left with a broken left leg.
Tennessee left tackle Taylor Lewan left his second game this season with an injury in the Titans' 13-12 loss in Buffalo. Lewan hurt a foot in the second quarter and was replaced by Tyler Marz. In Cincinnati, Miami left tackle Laremy Tunsil left with a concussion during the Bengals' fourth-quarter comeback.
Jets cornerback Buster Skrine started for Trumaine Johnson, sidelined with a strained quadriceps. But Skrine left in the first quarter with a head injury and did not return. Denver finished the 34-16 loss to the Jets without cornerback Adam Jones, who was ruled out in the second half after hurting a leg.
Cleveland wide receiver Rashard Higgins will have an MRI on Monday for a knee injury in the Browns' overtime victory over Baltimore. Higgins had three catches for 66 yards and a touchdown before getting hurt.
Detroit running back Kerryon Johnson ran for 70 yards on 12 carries before appearing to hurt his right ankle, and he left in the fourth quarter. Lions cornerback Teez Tabor (groin) and cornerback Jamal Agnew (knee) also left their 31-23 over Green Bay. Packers linebacker Nick Perry hurt an ankle, and cornerback Kevin King hurt his chin.
Giants right tackle Chad Wheeler did not return after hurting his hand in the fourth quarter of New York's 33-31 loss to Carolina. Panthers wide receiver Devin Funchess returned to the game after being evaluated for a concussion in the fourth quarter after a helmet-to-helmet hit by Giants defensive back Michael Thomas. Panthers center Ryan Kalil did not return after being shaken up late in the fourth quarter, with Tyler Larsen finishing the game.
The San Francisco 49ers, already reeling from quarterback Jimmy Garoppolo's season-ending knee injury, lost running back Matt Breida to an injured ankle in their 28-16 loss to Arizona. Breida entered fourth in the league in rushing with 313 yards and had eight carries for 56 yards, along with a TD catch, before he was hurt. Center Weston Richburg injured a knee and left in the second half.
The Cardinals' first victory of the season came with a price as two offensive linemen were hurt. Mike Iupati left with a shoulder injury and Andre Smith injured a hamstring.
In the Vikings' 23-21 road victory over the Super Bowl champion Philadelphia Eagles, left tackle Riley Reiff exited with a foot injury for Minnesota. Eagles safety Corey Graham left with a hamstring injury.
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