Barcelona midfielder Philippe Coutinho and Real Madrid left-back Marcelo have been dropped for Brazil's upcoming friendlies in England because of thigh injuries.
Beijing Guoan's Renato Augusto and Juventus' Alex Sandro will be their replacements for games against Uruguay in London on Nov. 16 and Cameroon in Milton Keynes on Nov. 20.
Coutinho, who has a left thigh injury, and Marcelo, who injured his right thigh, would have started the games.
Brazil could also lose another starter, Real Madrid defensive midfielder Casemiro, who has a right ankle injury during Real Madrid's visit to Celta Viga where Madrisitas won 4-2.
Casemiro left the match in the first half with a sprained right ankle, and Fernandez was substituted in the second with a dislocated ligament in his right knee.
The Brazil squad is set to train at Arsenal's ground later Monday.
Brazil's is focusing on the Copa America, which it will host next year.
(With AP Inputs)
