In order to keep main bowling spearhead Jimmy Anderson fir for the World Cup, England have kept him out of the squad due to tour Sri Lanka.
England's prize bowling asset was troubled by his left knee during the summer and was still feeling it when he joined up with the rest of the 50-over squad on Tuesday at the start of their three-day training camp in Loughborough.
Now he will miss the seven-match one-day series in Sri Lanka, which starts on November 26, along with his strike partner Stuart Broad, who is still recovering from an operation on his right knee.
England remain confident that both will be fit and ready for the World Cup in Australia and New Zealand in February but there will remain a question mark over both crucial figures until they are ready to bowl again.
Anderson has now been told to rest but hopes to continue his recovery in South Africa before Christmas with the England Performance Programme and if all goes well he will return for the triangular series that precedes the World Cup.
England do not plan to call up a replacement to face Sri Lanka, meaning more opportunities for the likes of Steven Finn, Chris Jordan, Chris Woakes and all-rounder Ben Stokes.