The U.S. Embassy spent $70,000 for advertisements on Pakistani TV that featured Obama and Secretary of State Hillary Rodham Clinton denouncing the video. Their comments, which are from previous public events in Washington, are in English but subtitled in Urdu, the main Pakistani language.
The deadliest violence occurred in the southern port city of Karachi, where 12 people were killed and 82 wounded, according to Seemi Jamali and Aftab Channar, officials at two hospitals.
Armed demonstrators among a crowd of 15,000 in that city fired on police, according to police officer Ahmad Hassan. The crowd also burned two cinemas and a bank, he said.
Three people were killed and 61 wounded in the northwestern city of Peshawar, said police official Bashir Khan. Police fired on rioters who set fire to two movie theaters and the city's chamber of commerce, and damaged shops and vehicles.
One of the dead was identified as Mohammad Amir, a driver for a Pakistani TV station who was killed when police bullets hit his vehicle, which was parked near the cinema, said Kashif Mahmood, a reporter for ARY TV who also was in the car. The TV channel showed doctors at a hospital trying unsuccessfully to save Amir's life.
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